学术报告会

Photonic Microsystems-on-Silicon for Biomedicine

¾ From Genetic Regulation, Cell Manipulation to Cancer Imaging

John X.J. Zhang, Ph.D.

Department of Biomedical Engineering

Microelectronics Research Center

The University of Texas at Austin, Austin, TX 78758

时间：6月3日上午10：00

地点：5号楼14层会议室

传感技术联合国家重点实验室 

Photonic Microsystems-on-Silicon for Biomedicine

¾ From Genetic Regulation, Cell Manipulation to Cancer Imaging

John X.J. Zhang, Ph.D.

Department of Biomedical Engineering

Microelectronics Research Center

The University of Texas at Austin, Austin, TX 78758

Phone: 512-475-6872   FAX: 512-471-8969

Email: John.Zhang@engr.utexas.edu

URL : http://www.bme.utexas.edu/research/zhang/

Translational biomedical engineering plays an important role in assimilating the advancement of device engineering towards developing innovative diagnosis, treatment and prevention of important human diseases at genetic, molecular and cellular levels. The micro-nano scale photonic tools for genetic regulation, cell manipulation, near field imaging, and in vivo microscopy contribute to the continuity of investigations across the biological hierarchy of multiple scales with minimal invasions, culminating in the understanding of whole body functions in health and disease. In this talk, I will review our research on exploring miniaturization technology and scale-dependent physical phenomena to (1) develop new diagnostic devices and methods on probing and regulating complex cellular processes and biological networks critical to development and disease, (2) develop light emitting quantum dots (QD) on near-field scanning probe tip for biomaterials imaging, and (3) most recently, develop nano-micro fabricated photonic sensors for molecular imaging and microscopy towards miniaturized endoscopic pre-cancer detection and diagnosis. Nano-Micro, Photon, and Bio are integrative components of our research, in which engineering expertise in photonic microsystems, nanotechnologies, and semiconductor physics is synergized to facilitate biomedical studies, and to obtain a better understanding of the fundamental problems in life science. This in turn benefits the advancement of engineering research.

Biographical Sketch

Dr. Zhang is a graduate of Stanford University, and was a Research Scientist at the Massachusetts Institute of Technology before joining the University of Texas of Austin in the Fall 2005. His research focuses on synergizing photonics and MEMS towards applications in materials imaging and characterization. He developed several unique methods to characterize multiscale biology-material interfaces using silicon photonic sensors on probe. His early efforts to provide massively parallel micrograting embedded cantilevers for force measurement on self-assembled cells may potentially lead to significant breakthroughs in genetic studies. His current research projects include silicon photonic crystal structures for nano-scale sensing, confocal scanners for in vivo molecular imaging, and nanoparticle based near-field microscopes. He received the Coulter Foundation Early Career Award in Biomedical Engineering in 2006.